The publication by Eva Böttcher-Friebertshäuser and her team on the front cover of the Journal of Biological Chemistry
On The Cover: The influenza virus glycoprotein hemagglutinin must be cleaved by host proteases to mediate fusion of viral and endosomal membranes, a prerequisite for virus replication. Harbig et al. investigated the trypsin-like serine protease repertoire of the lower airways of mice by RNA sequencing and used synthetic protease inhibitors like the shown benzylsulfonyl-D-Arg-Gly-4-amidinobenzylamide to identify appropriate influenza A and B virus–activating proteases. For details see the article by Harbig et al., pages 11388–11407.
Hector C. Aguilar and David W. Buchholz presesnt the article by Harbig et al. on JBC EDITORS’ PICK HIGHLIGHT.